KCNMB3 (82-207, His-tag) - AR51621PU-S

Product Description for KCNMB3

KCNMB3.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	BK channel subunit beta-3, Calcium-activated potassium channel, Calcium-activated potassium channel subunit beta-3, Charybdotoxin receptor subunit beta-3, K(VCA)beta-3, KCNMBL, Maxi K channel subunit beta-3, Slo-beta-3, subfamily M subunit beta-3
Presentation	Purified
Molecular weight	16.8 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9NPA1
Purity	> 85 % by SDS - PAGE
Background	The KCNMB3 is one of a family of four auxiliary beta subunits found in the mammalian genome that associate with Slo1 alpha subunits and regulate BK channel function. In humans, the KCNMB3 gene contains four N-terminal alternative exons that produce four functionally distinct beta3 subunits, beta3a-d. Three variants, beta3a-c, exhibit kinetically distinct inactivation behaviors.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Lee,U.S, et al. (2009) J. Physiol. (Lond.) 587 (PT 7), 1481-1498Zeng,X., et al. (2008) J. Gen. Physiol. 132 (1), 115-129
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human KCNMB3 fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSKPFMLSI QREESTCTAI HTDIMDDWLD CAFTCGVHCH GQGKYPCLQV FVNLSHPGQK ALLHYNEEAV QINPKCFYTP KCHQDRNDLL NSALDIKEFF DHKNGTPFSC FYSPASQSED VILIKKYDQ` Molecular weight: (149aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol Purity: >85% by SDS - PAGE State: Liquid purified protein Purified