Product Description for MYC-induced nuclear antigen
MYC-induced nuclear antigen.
Presentation: Purified
Presentation: Purified
Properties for MYC-induced nuclear antigen
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | MDIG, MINA, MINA53, Mineral dust-induced gene protein, NO52, Nucleolar protein 52 |
| Presentation | Purified |
| Molecular weight | 54.9 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | MINA is an oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. This protein is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. It also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. MINA may play an important role in cell growth and survival. It may be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Strausberg,R.L., et al. (2002) Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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