Product Description for SPRED1
SPRED1.
Presentation: Purified
Presentation: Purified
Properties for SPRED1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | EVH1/Sprouty domain containing protein, NFLS, Spred-1, Suppressor of Ras/MAPK activation |
| Presentation | Purified |
| Molecular weight | 52.9 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 80 % by SDS - PAGE |
| Background | SPRED1 is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. This protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Nonami A., et al. (2005) Genes Cells 10:887-895.King J.A.J., et al. (2005) Biochem. J. 388:445-454. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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