Product Description for ING1
ING1.
Presentation: Purified
Presentation: Purified
Properties for ING1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | ING-1, Inhibitor of growth protein 1 |
| Presentation | Purified |
| Molecular weight | 34.3 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. This protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Garkavtsev I.A., et al. (1998) Nature 391:295-298.Shi X., et al. (2006) Nature 442:96-99. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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