AR51666PU-N ELP4 (1-424, His-tag)

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0.5 mg / €820.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

ELP4

Product Description for ELP4

ELP4.
Presentation: Purified

Properties for ELP4

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms C11orf19, Elongator complex protein 4, PAX6 neighbor gene protein, PAXNEB
Presentation Purified
Molecular weight 49 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q96EB1
Purity > 80 % by SDS - PAGE
Background ELP4 is a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Strug,L.J., et al. (2009) Eur. J. Hum. Genet. 17 (9), 1171-1181.Miele,A., et al. (2007) J. Cell. Biochem. 102 (1), 136-148.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human ELP4 protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMAAVATC GSVAASTGSA VATASKSNVT SFQRRGPRAS VTNDSGPRLV SIAGTRPSVR NGQLLVSTGL PALDQLLGGG LAVGTVLLIE EDKYNIYSPL LFKYFLAEGI VNGHTLLVAS AKEDPANILQ ELPAPLLDDK CKKEFDEDVY NHKTPESNIK MKIAWRYQLL PKMEIGPVSS SRFGHYYDAS KRMPQELIEA SNWHGFFLPE KISSTLKVEP CSLTPGYTKL LQFIQNIIYE EGFDGSNPQK KQRNILRIGI QNLGSPLWGD DICCAENGGN SHSLTKFLYV LRGLLRTSLS ACIITMPTHL IQNKAIIARV TTLSDVVVGL ESFIGSERET NPLYKDYHGL IHIRQIPRLN NLICDESDVK DLAFKLKRKL FTIERLHLPP DLSDTVSRSS KMDLAESAKR LGPGCGMMAG GKKHLDF
Molecular weight:
(447aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Purity:
>80% by SDS - PAGE
State:
Liquid purified protein
Purified
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