GTF2H5 (1-71, His-tag) - AR51702PU-N

Product Description for GTF2H5

GTF2H5.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	C6orf175, General transcription factor IIH polypeptide 5, General transcription factor IIH subunit 5, TFB5 ortholog, TFIIH basal transcription factor complex TTD-A subunit, TTDA
Presentation	Purified
Molecular weight	10.4 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q6ZYL4
Purity	> 95 % by SDS - PAGE
Background	GTF2H5 is a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Giglia-Mari G., et al. (2004) Nat. Genet. 36:714-719
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human GTF2H5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMVNVLKG VLIECDPAMK QFLLYLDESN ALGKKFIIQD IDDTHVFVIA ELVNVLQERV GELMDQNAFS LTQK` Molecular weight: (94aa) confirmed by MALDI-TOF
Format	Buffer System: Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol. Purity: >95% by SDS - PAGE State: Purified