Product Description for MAP2K6
MAP2K6.
Presentation: Purified
Presentation: Purified
Properties for MAP2K6
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 20 µg |
| Synonyms | Dual specificity mitogen-activated protein kinase kinase 6, MAP kinase kinase 6, MAPK/ERK kinase 6, MAPKK 6, MEK6, MKK6, SAPKK3 |
| Presentation | Purified |
| Molecular weight | 32.0 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | MAP2K6 is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, MAP2K6 is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Manning G., et al. (2002) Science 298 (5600): 1912–34Pearson G., et al. (2002) Endocr. Rev. 22 (2): 153–83 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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