MICA (24-297, His-tag) - AR51873PU-N

Product Description for MICA

MICA.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.25 mg
Synonyms	MHC class I polypeptide-related sequence A, MIC-A, PERB11.1
Presentation	Purified
Molecular weight	32.7 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q29983
Purity	> 90 % by SDS - PAGE
Background	MICA also known as MHC class I polypeptide-related sequence A. This Protein’s Function seems to have no role in antigen presentation. It acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. It binding to KLRK1 leads to cell lysis.
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Strausberg, R.L, et al. (2002) Proc. Natl. Acad. Sci. u.S.A. 99 (26), 16899-16903
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human MICA, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MEPHSLRYNL TVLSWDGSVQ SGFLTEVHLD GQPFLRCDRQ KCRAKPQGQW AEDVLGNKTW DRETRDLTGN GKDLRMTLAH IKDQKEGLHS LQEIRVCEIH EDNSTRSSQH FYYDGELFLS QNLETEEWTM PQSSRAQTLA MNVRNFLKED AMKTKTHYHA MHADCLQELR RYLKSGVVLR RTVPPMVNVT RSEASEGNIT VTCRASGFYP WNITLSWRQD GVSLSHDTQQ WGDVLPDGNG TYQTWVATRI CQGEEQRFTC YMEHSGNHST HPVPSLEHHH HHH` Molecular weight: (283aa) confirmed by MALDI-TOF
Format	Buffer System: Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol, 1mM DTT. Purity: >90% by SDS - PAGE State: Liquid purified protein Purified