Product Description for Transglutaminase-2 (TGM2)
Transglutaminase-2 (TGM2).
Presentation: Purified
Presentation: Purified
Properties for Transglutaminase-2 (TGM2)
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Protein-glutamine gamma-glutamyltransferase 2, TGase C, TGase-H, Tissue transglutaminase |
| Presentation | Purified |
| Molecular weight | 79.4 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 85 % by SDS - PAGE |
| Background | Tgm2, also known as protein-glutamine gamma-glutamyltransferase 2 is calcium dependent enzyme of the protein-glutamine gamma-glutamyltransferases family. Like other transglutaminases, it crosslinks proteins between an epsilon-amino group of a lysine residue and a gamma-carboxamide group of glutamine residue, creating an inter- or intramolecular bond that is highly resistant to proteolysis (protein degradation). Aside from its crosslinking function, tTG catalyzes other types of reactions including deamidation, GTP-binding/hydrolyzing, and isopeptidase activities. unlike other members of the transglutaminase family, tTG can be found both in the intracellular and the extracellular spaces of various types of tissues and is found in many different organs including the heart, the liver, and the small intestine. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Nanda N., et al. (1999) Arch. Biochem. Biophys. 366:151-156 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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