IL1F10 / FIL1T (1-152, ) - AR51864PU-N

Product Description for IL1F10 / FIL1T

IL1F10 / FIL1T.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	FKSG75, IL-1F10, IL1HY2, Interleukin-1 HY2, Interleukin-1 family member 10, Interleukin-1 receptor antagonist-like FIL1 theta
Presentation	Purified
Molecular weight	16.9 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q8WWZ1
Purity	> 95 % by SDS - PAGE
Background	IL1F10 also known as interleukin-1 family member 10. IL1F10 is cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. It reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. It increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS) and ligand for IL-36R/IL1RL2. Recombinant human IL1F10 was expressed in E.coli and purified by using conventional chromatography techniques
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Bensen J.T., et al. (2001) J. Interferon Cytokine Res. 21:899-904.van de Veerdonk F.L., et al. (2012) Proc. Natl. Acad. Sci. u.S.A. 109:3001-3005.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	AA Sequence: `MCSLPMARYY IIKYADQKAL YTRDGQLLVG DPVADNCCAE KICTLPNRGL DRTKVPIFLG IQGGSRCLAC VETEEGPSLQ LEDVNIEELY KGGEEATRFT FFQSSSGSAF RLEAAAWPGW FLCGPAEPQQ PVQLTKESEP SARTKFYFEQ SW` Molecular weight: (152aa) confirmed by MALDI-TOF
Format	Buffer System: Phosphate buffered saline (pH7.4). Purity: >95% by SDS - PAGE State: Liquid purified protein Purified