TECK / CCL25 (His-tag) - AR51817PU-N

Product Description for TECK / CCL25

TECK / CCL25.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	C-C motif chemokine 25, Chemokine TECK, SCYA25, Small-inducible cytokine A25, Thymus-expressed chemokine
Presentation	Purified
Molecular weight	16.8 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: O15444
Purity	> 90 % by SDS - PAGE
Background	CCL25 also known as C-C motif chemokine 25 isoform 1. CCL25 is potentially involved in T-cell development.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Watts A.O. et al. (2013) J. Biol. Chem. 288:7169-7181.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. It binds to CCR9. Isoform 2 is an antagonist of isoform1 and binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. Recombinant human CCL25-iso1, fused to His-tag at N-terminus, was expressed in E.coli . AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSHMQGVFE DCCLAYHYPI GWAVLRRAWT YRIQEVSGSC NLPAAIFYLP KRHRKVCGNP KSREVQRAMK LLDARNKVFA KLHHNTQTFQ AGPHAVKKLS SGNSKLSSSK FSNPISSSKR NVSLLISANS GL` Molecular weight: (152aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol. Purity: >90% by SDS - PAGE State: Liquid purified protein Purified