Product Description for Cathepsin L1
Cathepsin L1.
Presentation: Purified
Presentation: Purified
Properties for Cathepsin L1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein |
| Presentation | Purified |
| Molecular weight | 38.3 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | CTSL, also known as Cathepsin L1 isoform 1 preproprotein, is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Bauer Y, Hess P, et al. (2011). Hypertension. 57(4):795-801.Wei DH, Jia XY, et al. (2013). Int J Mol Med. 31(2):400-6. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Description |
|
| Format |
|
Compare Products
You have no items to compare.
My Cart
You have no items in your shopping cart.
