Product Description for CD80
Hamster anti Mouse CD80 MAB0713.
Presentation: Purified
Product is tested for Paraffin Sections, Flow Cytometry.
Presentation: Purified
Product is tested for Paraffin Sections, Flow Cytometry.
Properties for CD80
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80 |
| Presentation | Purified |
| Reactivity | Ms |
| Applications | F, P |
| Clonality | Monoclonal |
| Clone | MAB0713 |
| Host | Hamster |
| Isotype | IgG |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Monoclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Application | Immunohistochemistry on Paraffin Sections: 1/100-1/300. Flow Cytometry: 1/100-1/1000. |
| Background | B7-1 (CD80) and B7-2, together with their receptors CD28 and CTLA4, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. Although both CTLA4 and CD28 can bind to the same ligands, CTLA4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the downregulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. Additionally, B7-2 is expressed at low levels on monocytes and can be upregulated through interferon gamma. B7-1 and B7-2 are both members of the Immunoglobulin superfamily. |
| Storage | Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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Accessory Products
Recommended Secondary Antibodies for CD80 (8 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1327AP |
Hamster IgG (H+L chain) antibody |
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|
Rabbit | AP | |||||
| OriGene Technologies GmbH | |||||||
| R1327B |
Hamster IgG (H+L chain) antibody |
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|
|
Rabbit | Biotin | |||||
| OriGene Technologies GmbH | |||||||
| R1327F |
Hamster IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | |||||
| OriGene Technologies GmbH | |||||||
| R1327HRP |
Hamster IgG (H+L chain) antibody |
||||||
|
|
Rabbit | HRP | |||||
| OriGene Technologies GmbH | |||||||
| R1327T |
Hamster IgG (H+L chain) antibody |
||||||
|
|
Rabbit | TRITC | |||||
| OriGene Technologies GmbH | |||||||
| R1437C2 |
Hamster IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1437C3 |
Hamster IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1437C5 |
Hamster IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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