AR31171PU-N IFNB / Interferon beta

Search for all "IFNB / Interferon beta"

20 µg / €330.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

IFNB / Interferon beta

AR31171PU-N

Product Description for IFNB / Interferon beta

IFNB / Interferon beta.
Presentation: Purified

Properties for IFNB / Interferon beta

Product Category Proteins & Growth Factors
Quantity 20 µg
Synonyms Fibroblast interferon, IFB, IFN-beta, IFNB1
Presentation Purified
Molecular weight 22.3 kDa
Source CHO cells
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P01574
Purity > 95 % by SDS-PAGE and HPLC
Background Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-alpha is an acid stable molecule that signals through IFN-alpha/betaR, which is also used by IFN-beta. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFN-alpha contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity.
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant Human IFN-beta is a 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFN-beta has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry.
AA Sequence:
MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN
Biological activity:
Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8).”
Format
Stabilizers:
None
Endotoxin level:
< 0.1 ng per µg of IFN-beta
Purity:
>95% by SDS-PAGE and HPLC
State:
Lyophilized purified protein
Purified
Reconstitution:
Restore in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C.
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