discontinued

AM00201PU-N Clostridium difficile Toxin A antibody

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Mouse anti Clostridium difficile Toxin A 5157

AM00201PU-N

Product Description for Clostridium difficile Toxin A

Mouse anti Clostridium difficile Toxin A 5157.
Presentation: Purified
Product is tested for Enzyme Immunoassay.

Properties for Clostridium difficile Toxin A

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms tcdA, toxA
Presentation Purified
Applications E
Clonality Monoclonal
Clone 5157
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P16154
Immunogen:
Clostridium difficile toxin A.
Isotype control AM03095PU-N
Application ELISA: 1/20-1/200.
Background Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics.
Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.
Concentration 0.1 mg/ml
General Readings
  1. Voth DE, Ballard JD. Clostridium difficile toxins: mechanism of action and role in disease. Clin Microbiol Rev. 2005 Apr;18(2):247-63. PubMed PMID: 15831824. (Free PMC Article available, 3 images available)
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography on Protein A
Buffer System:
PBS, pH 7.2
Preservatives:
0.09% Sodium Azide
State:
Liquid purified IgG faction from Tissue Culture Supernatant
Purified
Specificity
Specificity:
Specific for Clostridium difficile toxin A.
No reaction is observed with the following organisms: Clostridium difficile toxin B, tetanus toxoid, Pseudomonas aeruginosa and Yersinia enterocolitica.

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