Product Description for HPA-5b
Human anti Human HPA-5b F2H11.
Presentation: Alexa Fluor 647
Product is tested for Immunocytochemistry/Immunofluorescence, Flow Cytometry.
Presentation: Alexa Fluor 647
Product is tested for Immunocytochemistry/Immunofluorescence, Flow Cytometry.
Properties for HPA-5b
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 50 µg |
| Synonyms | human platelet antigen 5b |
| Presentation | Alexa Fluor 647 |
| Reactivity | Hu |
| Applications | F, ICC/IF |
| Clonality | Monoclonal |
| Clone | F2H11 |
| Host | Human |
| Isotype | IgG1 |
| Shipping to | Germany, USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Dendritics SAS |
Datasheet Extract
| Immunogen |
|
|---|---|
| Application | Platelet phenotyping by flow cytometry, IF, ELISA, platelet aggregation studies. Usage recommendation: *This monoclonal antibody may be used between 5-25μg/ml. *Optimal dilution should be determined by each laboratory for each application. *Coupled antibody: to maintain RT before use. |
| Background | Neonatal AlloImmune Thrombocytopenia (NAIT) is the commonest cause of severe isolated thrombocytopenia in the foetus and newborn. In Caucasians, 97% of NAIT are caused by HPA-1a or HPA- 5b alloantibodies. B4F12 was isolated after combination of CD40 activation and Epstein-Barr virus transformation of B cells isolated from a woman with high titre of anti -HPA-5b alloantibodies. B4F12 human monoclonal antibody recognizes GPIa-IIa preferentially on activated human platelets (Mérieux Y, Rigal D, Pin JJ, XVIIth Regional Congress, International Society of Blood Transfusion, Madrid 2007 ; Guillot-Chene P, Lebecque S, Rigal D, Annales Pharmaceutiques Françaises, 06/2009, 67 (3) 182-6). |
| Concentration | 0.5 mg/ml |
| Product Citations |
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| Storage | -20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing. |
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Accessory Products
Proteins and/or Positive Controls
Proteins for HPA-5b (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00003673-Q01-10 |
CD49b / ITGA2 |
||||||
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue | |||||
| Abnova Taiwan Corp. | |||||||
| H00003673-Q01-25 |
CD49b / ITGA2 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue | |||||
| Abnova Taiwan Corp. | |||||||
Positive controls for HPA-5b (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-12062 |
Integrin alpha 2 Lysate |
||||||
![Western Blot: Integrin alpha 2 Lysate [NBL1-12062] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for ITGA2](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Integrin%20alpha%202%20Lysate-Western%20Blot-NBL1-12062-img0001.jpg) |
|||||||
| Novus Biologicals Inc. | |||||||
| LY400802 |
ITGA2 overexpression lysate |
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|
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| OriGene Technologies, Inc. | |||||||
Recommended Secondary Antibodies for HPA-5b (0 products)
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