Product Description for Cyclophilin F
Cyclophilin F.
Presentation: Purified
Presentation: Purified
Properties for Cyclophilin F
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | CYP3, PPIF, PPIase F, Rotamase F, mitochondrial Peptidyl-prolyl cis-trans isomerase |
| Presentation | Purified |
| Molecular weight | 21.2 Da |
| Source | E. coli |
| Species (Protein) | Rat |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | Ppif also known as Peptidyl-prolyl cis-trans isomerase F, mitochondrial. Ppif accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis the requirement of the PPIase activity for this function is debated. |
| Concentration | 1.0 mg/ml (determined by absorbance at 280nm) |
| General Readings | Connern C.P., et al. (1992) Biochem. J. 284:381-385.Lin DT., et al. (2002) J Biol Chem. 23:277(34):31134-41. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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