AR51951PU-N Aminoacylase-1 / ACY1 (1-408, His-tag)

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0.1 mg / €820.00
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Aminoacylase-1 / ACY1

Product Description for Aminoacylase-1 / ACY1

Aminoacylase-1 / ACY1.
Presentation: Purified

Properties for Aminoacylase-1 / ACY1

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms ACY-1, N-acyl-L-amino-acid amidohydrolase
Presentation Purified
Molecular weight 48.4 kDa
Source E. coli
Species (Protein) Mouse
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q99JW2
Purity > 90 % by SDS - PAGE
Background Acy1 also known as Aminoacylase1. The protein is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors.
Concentration 0.25 mg/ml (determined by absorbance at 280nm)
General Readings Miller YE, Drabkin H, et al. (1991) Genomics 8 (1): 149-154. Voss R, et al. (1982) Ann Hum Genet 44 (Pt 1): 1-9.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant mouse Acy1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSEFMTTKD PESEHPSVTL FRQYLRICTV QPNPDYGGAI TFLEERARQL GLSCQKIEVV PGFVITVLTW PGTNPSLPSI LLNSHTDVVP VFKEHWHHDP FEAFKDSEGY IYARGSQDMK SVSIQYLEAV RRLKSEGHRF PRTIHMTFVP DEEVGGHKGM ELFVKRPEFQ ALRAGFALDE GLANPTDAFT VFYSERSPWW VRVTSTGKPG HASRFIEDTA AEKLHKVISS ILAFREKERQ RLQANPHLKE GAVTSVNLTK LEGGVAYNVV PATMSASFDF RVAPDVDMKA FEKQLQRWCQ EAGEGVTFEF AQKFTEPRMT PTDDSDPWWA AFSGACKAMN LTLEPEIFPA ATDSRYIRAV GIPALGFSPM NRTPVLLHDH NERLHEDIFL RGVDIYTGLL SALASVPTLP GES
Molecular weight:
(433aa), confirmed by MALDI-TOF
Format
Buffer System:
Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol.
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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