AR51900PU-S Interleukin-28B (22-196, His-tag)

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50 µg / €320.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Interleukin-28B

Product Description for Interleukin-28B

Interleukin-28B.
Presentation: Purified

Properties for Interleukin-28B

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms IFN-lambda-3, Ifnl3, Il28, Il28b, Interferon lambda-3
Presentation Purified
Molecular weight 20.4 kDa
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q8IZI9
Purity > 85 % by SDS - PAGE
Background IFNL3, also known as Interferon lambda-3, is a secreted protein which belongs to the IL-28/IL-29 family. It is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. This protein displays potent antiviral activity and antitumor activity. It seems to signal through the Jak-STAT pathway. It also contributes to viral resistance and is known to be upregulated by interferons and by RNA virus infection.
Concentration 0.25 mg/ml (determined by bradford assay)
General Readings
  • Kamal SM. et al. (2014) Am J Gastroenterol. 109(2):199-211.
  • Frizon K. et al. (2014) Braz J Infect Dis. 18(2):229-30.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human IFNL3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
AA Sequence:
VPVARLRGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCKC RSRLFPRTWD LRQLQVRERP VALEAELALT LKVLEATADT DPALGDVLDQ PLHTLHHILS QLRACIQPQP TAGPRTRGRL HHWLHRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCVHHHHH H
Molecular weight:
(181aa)
Format
Buffer System:
Phosphate buffered saline (pH 7.4) containing 20% Glycerol, 1mM EDTA, 0.1mM PMSF
Endotoxin level:
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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