Product Description for LRPAP1 / A2MRAP
LRPAP1 / A2MRAP.
Presentation: Purified
Presentation: Purified
Properties for LRPAP1 / A2MRAP
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | Alpha-2-MRAP, Alpha-2-macroglobulin receptor-associated protein, Low density lipoprotein receptor-related protein-associated protein 1, RAP |
| Presentation | Purified |
| Molecular weight | 41.4 kDa |
| Source | E. coli |
| Species (Protein) | Mouse |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | Lrpap1 also known as Alpha-2-macroglobulin receptor-associated protein. The alpha-2-macroglobulin receptor-associated protein (RAP) is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. Lrpap1 acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. Lrpap1 may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II. |
| Concentration | 1.0 mg/ml (determined by absorbance at 280nm) |
| General Readings | Strickland D.K., et al. (1991) J. Biol. Chem. 266:13364-13369. Van Leuven F., et al. (1998) Genomics 52:145-151. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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