AR51940PU-S MAPK8 / JNK1 (1-427, His-tag)

Search for all "MAPK8 / JNK1"

0.1 mg / €320.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

MAPK8 / JNK1

Product Description for MAPK8 / JNK1

MAPK8 / JNK1.
Presentation: Purified

Properties for MAPK8 / JNK1

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms JNK-1, JNK-46, Mitogen-activated protein kinase 8, PRKM8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1
Presentation Purified
Molecular weight 50.5 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P45983
Purity > 85 % by SDS - PAGE
Background MAPK8 also known as mitogen-activated protein kinase 8 JNK beta 2. MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli.
Concentration 0.5 mg/ml (determined by absorbance at 280nm)
General Readings Jha A., et al. (2014) EMBO J. 33 (5), 501-511Misheva M., et al. (2014) Biochim. Biophys. Acta 1843 (2), 253-264
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human MAPK8, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMSRSKRD NNFYSVEIGD STFTVLKRYQ NLKPIGSGAQ GIVCAAYDAI LERNVAIKKL SRPFQNQTHA KRAYRELVLM KCVNHKNIIG LLNVFTPQKS LEEFQDVYIV MELMDANLCQ VIQMELDHER MSYLLYQMLC GIKHLHSAGI IHRDLKPSNI VVKSDCTLKI LDFGLARTAG TSFMMTPYVV TRYYRAPEVI LGMGYKENVD IWSVGCIMGE MIKGGVLFPG TDHIDQWNKV IEQLGTPCPE FMKKLQPTVR TYVENRPKYA GYSFEKLFPD VLFPADSEHN KLKASQARDL LSKMLVIDAS KRISVDEALQ HPYINVWYDP SEAEAPPPKI PDKQLDEREH TIEEWKELIY KEVMDLEERT KNGVIRGQPS PLGAAVINGS QHPSSSSSVN DVSSMSTDPT LASDTDSSLE AAAGPLGCCR
Molecular weight:
(450aa)
Format
Buffer System:
Phosphate Buffer Saline (pH7.4) containing 20% glycerol, 1mM DTT.
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
  • LinkedIn