AR51902PU-S CD212 / IL12RB1 (24-545, His-tag)

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50 µg / €320.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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CD212 / IL12RB1

Product Description for CD212 / IL12RB1

CD212 / IL12RB1.
Presentation: Purified

Properties for CD212 / IL12RB1

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms IL-12 receptor beta, IL-12R-beta-1, IL-12RB1, IL12 receptor beta component, Interleukin-12 receptor beta-1 chain
Presentation Purified
Molecular weight 58.4 kDa
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P42701
Purity > 90 % by SDS - PAGE.
Background IL12RB1, also known as Interleukin-12 receptor subunit beta-1, is a intercellular adhesion molecule 1. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. It forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this protein and IL12RB2 was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling.
Concentration 0.25 mg/ml (determined by bradford assay)
General Readings van de Vosse E. et al. (2003) Immunogenetics. 54(12):817-29.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human IL12RB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
AA Sequence:
CRTSECCFQD PPYPDADSGS ASGPRDLRCY RISSDRYECS WQYEGPTAGV SHFLRCCLSS GRCCYFAAGS ATRLQFSDQA GVSVLYTVTL WVESWARNQT EKSPEVTLQL YNSVKYEPPL GDIKVSKLAG QLRMEWETPD NQVGAEVQFR HRTPSSPWKL GDCGPQDDDT ESCLCPLEMN VAQEFQLRRR QLGSQGSSWS KWSSPVCVPP ENPPQPQVRF SVEQLGQDGR RRLTLKEQPT QLELPEGCQG LAPGTEVTYR LQLHMLSCPC KAKATRTLHL GKMPYLSGAA YNVAVISSNQ FGPGLNQTWH IPADTHTEPV ALNISVGTNG TTMYWPARAQ SMTYCIEWQP VGQDGGLATC SLTAPQDPDP AGMATYSWSR ESGAMGQEKC YYITIFASAH PEKLTLWSTV LSTYHFGGNA SAAGTPHHVS VKNHSLDSVS VDWAPSLLST CPGVLKEYVV RCRDEDSKQV SEHPVQPTET QVTLSGLRAG VAYTVQVRAD TAWLRGVWSQ PQRFSIEVQV SDHHHHHH
Molecular weight:
(528aa)
Format
Buffer System:
Phosphate buffered saline (pH 7.4) containing 20% glycerol, 1mM EDTA, 0.1mM PMSF.
Endotoxin level:
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity:
>90% by SDS - PAGE.
State:
Liquid purified protein
Purified
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