Product Description for Carbonic anhydrase 12
Carbonic anhydrase 12.
Presentation: Purified
Presentation: Purified
Properties for Carbonic anhydrase 12
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | CA-XII, CA12, Carbonate dehydratase XII, Carbonic anhydrase XII, HOM-RCC-3.1.3 tumor antigen |
| Presentation | Purified |
| Molecular weight | 31.94 kDa |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | CA12, also known as Carbonic anhydrase 12, is an enzyme that in humans is encoded by the CA12 gene. Carbonic anhydrases(CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. |
| Concentration | 0.5 mg/ml (determined by absorbance at 280nm) |
| General Readings | Tureci O. et al. (1998) Proc Natl Acad Sci U S A. 95(13):7608-13.Kyllonen MS. et al. (2003) J Histochem Cytochem. 51(9):1217-24. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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