Product Description for Human IgE
Presentation: Purified
Product is tested for Enzyme Immunoassay, Flow Cytometry.
Product is tested for Enzyme Immunoassay, Flow Cytometry.
Properties for Human IgE
| Product Category | Secondary Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Immunoglobulin E human |
| Presentation | Purified |
| Reactivity | Hu |
| Applications | E, F |
| Clonality | Monoclonal |
| Clone | BE5 |
| Host | Mouse |
| Isotype | IgG1 |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Monoclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Isotype control | AM03095PU-N, SM10P (for use in human samples) |
| Application | ELISA. Flow Cytometry: 5-10 µg/ml. |
| Background | Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion. |
| Concentration | 1.0 mg/ml |
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| Storage | Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch. |
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