TNFRSF18 / GITR (26-162, His-tag) - AR51970PU-S

Product Description for TNFRSF18 / GITR

TNFRSF18 / GITR.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	50 µg
Synonyms	AITR, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, Tumor necrosis factor receptor superfamily member 18
Presentation	Purified
Molecular weight	15.6 kDa
Source	Insect cells
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9Y5U5
Purity	> 95 % by SDS - PAGE
Background	TNFRSF18, also known as tumor necrosis factor receptor superfamily member 18, belongs to the tumor necrosis factor receptor superfamily. It is receptor for TNFSF18 and seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It is mediated NF-kappa-B activation via the TRAF2/NIK pathway. Recombint human TNFRSF18, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventiol chromatography techniques.
Concentration	0.5 mg/ml (determined by absorbance at 280nm)
General Readings	Gurney A.L., et al. (1999) Curr. Biol. 9:215-218.Kwon B., et al. (1999) J.Biol. Chem. 274:6056-6061.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	AA Sequence: `QRPTGGPGCG PGRLLLGTGT DARCCRVHTT RCCRDYPGEE CCSEWDCMCV QPEFHCGDPC CTTCRHHPCP PGQGVQSQGK FSFGFQCIDC ASGTFSGGHE GHCKPWTDCT QFGFLTVFPG NKTHNAVCVP GSPPAEPLEH HHHHH` Molecular weight: (145aa)
Format	Buffer System: Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. Endotoxin level: < 1.0 EU per 1 microgram of protein (determined by LAL method) Purity: >95% by SDS - PAGE State: Liquid purified protein Purified