Product Description for Erythropoietin / EPO
Erythropoietin / EPO.
Presentation: Purified
Presentation: Purified
Properties for Erythropoietin / EPO
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | Epoetin |
| Presentation | Purified |
| Molecular weight | 19.5 kDa |
| Source | Insect cells |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 95 % by SDS - PAGE |
| Background | EPO, also known as erythropoietin, is a glycoprotein hormone in the type I cytokine family and is related to thrombopoietin. Its three N-glycosylation sites, four alpha helices, and N- to C-termil disulfide bond are conserved across species. It is primarily produced in the kidney by a population of fibroblast-like cortical interstitial cells adjacent to the proximal tubules. This protein can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and anti-apoptotic functions in several tissue types. Recombint human EPO, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventiol chromatography techniques. |
| Concentration | 0.5 mg/ml (determined by absorbance at 280nm) |
| General Readings | Koury, M.J., et al. (2005) Exp. Hematol. 33:1263.Jelkmann W., et al. (2007) Eur J Haematol. 78:183-205 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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