Product Description for PIAS2
Rabbit anti Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat PIAS2.
Presentation: Purified
Product is tested for Western blot / Immunoblot.
Presentation: Purified
Product is tested for Western blot / Immunoblot.
Properties for PIAS2
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 0.1 ml |
| Synonyms | ARIP3, Androgen receptor-interacting protein 3, DAB2-interacting protein, DIP, E3 SUMO-protein ligase PIAS2, Miz1, Msx-interacting zinc finger protein, PIAS-NY protein, PIASX, Protein inhibitor of activated STAT x, Protein inhibitor of activated STAT2 |
| Presentation | Purified |
| Reactivity | Bov, Can, Eq, Hu, Ms, Por, Rb, Rt |
| Applications | WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Europe, USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies, Inc. |
Datasheet Extract
| Immunogen |
|
|---|---|
| Application | WB |
| Background | Pias2 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. It plays a crucial role as a transcriptiol coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone sigling pathway. It seems to be mostly involved in gene silencing. It binds to sumoylated ELK1 and enhances its transcriptiol activity by preventing recruitment of HDAC2 by ELK1, thus reversing SUMO-mediated repression of ELK1 transactivation activity. This gene encodes a protein involved in the regulation of transcription factors involved in MAP kise sigling. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. Two altertively spliced transcripts encoding different isoforms have been described. |
| Format |
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Accessory Products
Proteins and/or Positive Controls
Proteins for PIAS2 (10 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| TP760271 |
PIAS2 (full length, N-term HIS tag, transcript variant beta) |
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|
Human |
> 80 % Preparation: . Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
50 µg /
€205.00
|
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| OriGene Technologies, Inc. | |||||||
| H00009063-P01 |
PIAS2 |
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|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| H00009063-P01-10 |
PIAS2 |
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|
|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
| Abnova Taiwan Corp. | |||||||
| H00009063-P01-25 |
PIAS2 |
||||||
|
|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
| Abnova Taiwan Corp. | |||||||
| H00009063-Q01-10 |
PIAS2 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| H00009063-Q01-25 |
PIAS2 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| P0311 |
PIAS2 |
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|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P0312 |
PIAS2 |
||||||
|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P0314 |
PIAS2 |
||||||
|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P0328 |
PIAS2 |
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|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
Positive controls for PIAS2 (5 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00009063-T01 |
PIAS2 293T Cell Transient Overexpression Lysate(Denatured) |
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|
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| Abnova Taiwan Corp. | |||||||
| NBL1-14385 |
PIAS2 Lysate |
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![Western Blot: PIAS2 Lysate [NBL1-14385] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for PIAS2](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/PIAS2%20Lysate-Western%20Blot-NBL1-14385-img0001.jpg) |
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| Novus Biologicals Inc. | |||||||
| NBL1-14386 |
PIAS2 Lysate |
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![Western Blot: PIAS2 Lysate [NBL1-14386] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for PIAS2](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/PIAS2%20Lysate-Western%20Blot-NBL1-14386-img0001.jpg) |
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| Novus Biologicals Inc. | |||||||
| LY401487 |
PIAS2 overexpression lysate |
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|
0.1 mg /
€495.00
|
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| OriGene Technologies, Inc. | |||||||
| LY406651 |
PIAS2 overexpression lysate |
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|
0.1 mg /
€295.00
|
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| OriGene Technologies, Inc. | |||||||
Recommended Secondary Antibodies for PIAS2 (9 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | Rb | E, ICC/IF, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | Rb | E, P, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | Rb | E, F, ICC/IF | |||
| OriGene Technologies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | Rb | F | |||
| OriGene Technologies GmbH | |||||||
| R1458C2 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C3 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C5 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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