Product Description for Glutaredoxin-2 / GLRX2
Rabbit anti Bovine, Canine, Equine, Guinea Pig, Human, Mouse, Porcine, Rabbit Glutaredoxin-2 / GLRX2.
Presentation: Purified
Product is tested for Western blot / Immunoblot.
Presentation: Purified
Product is tested for Western blot / Immunoblot.
Properties for Glutaredoxin-2 / GLRX2
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 0.1 ml |
| Synonyms | GRX2, Glutaredoxin-2 mitochondrial, grxB |
| Presentation | Purified |
| Reactivity | Bov, Can, Eq, GP, Hu, Ms, Por, Rb |
| Applications | WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Europe, USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies, Inc. |
Datasheet Extract
| Immunogen |
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|---|---|
| Application | WB |
| Background | GLRX2 is a glutathione-dependent oxidoreductase that facilitates the maintence of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress.GLRX2 is involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress.GLRX2 acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides.GLRX2 can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions.GLRX2 efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression of GLRX2 decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release. |
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Accessory Products
Proteins and/or Positive Controls
Proteins for Glutaredoxin-2 / GLRX2 (7 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| TP315566 |
Glutaredoxin-2 / GLRX2 (transcript variant 1) |
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|
Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
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| OriGene Technologies, Inc. | |||||||
| AR09319PU-L |
Glutaredoxin-2 / GLRX2 (20-164, His-tag) |
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|
Human | Purified | > 90 % by SDS - PAGE | E. coli |
0.5 mg /
€720.00
|
||
| OriGene Technologies GmbH | |||||||
| AR09319PU-N |
Glutaredoxin-2 / GLRX2 (20-164, His-tag) |
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|
|
Human | Purified | > 90 % by SDS - PAGE | E. coli |
0.1 mg /
€290.00
|
||
| OriGene Technologies GmbH | |||||||
| H00051022-P01-10 |
Glutaredoxin-2 / GLRX2 |
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|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| H00051022-P01-25 |
Glutaredoxin-2 / GLRX2 |
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|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| P4549 |
Glutaredoxin-2 / GLRX2 |
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|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| NBP1-30299 |
Glutaredoxin-2 / GLRX2 |
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![SDS-Page: Glutaredoxin 2 Protein [NBP1-30299] - Glutaredoxin-2, 17.0 kDa (154aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Glutaredoxin%202%20Protein-SDS-Page-NBP1-30299-img0001.jpg)
|
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| Novus Biologicals Inc. | |||||||
Positive controls for Glutaredoxin-2 / GLRX2 (3 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00051022-T01 |
GLRX2 293T Cell Transient Overexpression Lysate(Denatured) |
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|
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| Abnova Taiwan Corp. | |||||||
| H00051022-T02 |
GLRX2 293T Cell Transient Overexpression Lysate(Denatured) |
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|
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| Abnova Taiwan Corp. | |||||||
| LY414214 |
GLRX2 overexpression lysate |
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|
0.1 mg /
€295.00
|
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| OriGene Technologies, Inc. | |||||||
Recommended Secondary Antibodies for Glutaredoxin-2 / GLRX2 (9 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
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|
|
Goat | AP | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
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|
|
Goat | Biotin | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | Rb | E, ICC/IF, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | Rb | E, P, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | Rb | E, F, ICC/IF | |||
| OriGene Technologies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
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|
|
Donkey | PE | Rb | F | |||
| OriGene Technologies GmbH | |||||||
| R1458C2 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C3 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C5 |
Rabbit IgG (H+L chain, adsorbed) antibody |
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|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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