Product Description for PCBP1
Rabbit anti Bovine, Canine, Equine, Guinea Pig, Human, Mouse, Rabbit, Rat PCBP1.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.
Properties for PCBP1
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 0.1 ml |
| Synonyms | Alpha-CP1, HNRPE1, HNRPX, Heterogeneous nuclear ribonucleoprotein E1, Nucleic acid-binding protein SUB2.3, Poly(rC)-binding protein 1, SUB2.3, hnRNP E1 |
| Presentation | Purified |
| Reactivity | Bov, Can, Eq, GP, Hu, Ms, Rb, Rt |
| Applications | P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Europe, USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies, Inc. |
Datasheet Extract
| Immunogen |
|
|---|---|
| Application | IHC WB |
| Background | PCBP1 appears to be multifunctiol. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in R binding. This protein together with PCBP-2 also functions as translatiol coactivators of poliovirus R via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus R replication by binding to its 5'-termil cloverleaf structure. It has also been implicated in translatiol control of the 15-lipoxygese mR, human Papillomavirus type 16 L2 mR, and hepatitis A virus R. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mR stability.This intronless gene is thought to be generated by retrotransposition of a fully processed PCBP-2 mR. This gene and PCBP-2 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctiol. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. It contains three K-homologous (KH) domains which may be involved in R binding. This encoded protein together with PCBP-2 also functions as translatiol coactivators of poliovirus R via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus R replication by binding to its 5'-termil cloverleaf structure. It has also been implicated in translatiol control of the 15-lipoxygese mR, human Papillomavirus type 16 L2 mR, and hepatitis A virus R. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mR stability. |
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Accessory Products
Proteins and/or Positive Controls
Proteins for PCBP1 (7 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| TP307878 |
PCBP1 |
||||||
|
Human |
> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|||
| OriGene Technologies, Inc. | |||||||
| AR51138PU-N |
PCBP1 (1-163, His-tag) |
||||||
|
Human | Purified | > 85 % by SDS - PAGE | E. coli |
0.5 mg /
€820.00
|
||
| OriGene Technologies GmbH | |||||||
| AR51138PU-S |
PCBP1 (1-163, His-tag) |
||||||
|
|
Human | Purified | > 85 % by SDS - PAGE | E. coli |
0.1 mg /
€320.00
|
||
| OriGene Technologies GmbH | |||||||
| H00005093-P01-10 |
PCBP1 |
||||||
|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
| Abnova Taiwan Corp. | |||||||
| H00005093-P01-25 |
PCBP1 |
||||||
|
|
Human | Purified | 12.5% SDS-PAGE Stained with Coomassie Blue. | ||||
| Abnova Taiwan Corp. | |||||||
| H00005093-Q01-10 |
PCBP1 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| H00005093-Q01-25 |
PCBP1 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
Positive controls for PCBP1 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-14142 |
PCBP1 Lysate |
||||||
![Western Blot: PCBP1 Lysate [NBL1-14142] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for PCBP1.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/PCBP1%20Lysate-Western%20Blot-NBL1-14142-img0001.jpg) |
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| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for PCBP1 (9 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | Rb | E, ICC/IF, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | Rb | E, P, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | Rb | E, F, ICC/IF | |||
| OriGene Technologies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | Rb | F | |||
| OriGene Technologies GmbH | |||||||
| R1458C2 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C3 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C5 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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