Product Description for Epstein Barr Virus / EBV
Rat anti Epstein Barr Virus / EBV 14B7.
Properties: LMP2A
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot.
Properties: LMP2A
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot.
Properties for Epstein Barr Virus / EBV
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | HHV-4, HHV4 |
| Presentation | Purified |
| Applications | ICC/IF, IP, WB |
| Clonality | Monoclonal |
| Clone | 14B7 |
| Host | Rat |
| Isotype | IgG2a |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Monoclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Property | LMP2A |
| Isotype control | SM15P, SM15PX |
| Application | Immunoprecipitation. Immunofluorescence. Western Blot: 1/100 - 1/1000. Not suitable for paraffin sections. |
| Background | EBV is a human herpesvirus, which is associated with conditions such as Hodgkins disease and Burkitts Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. Clone 14B7 detects wild-type LMP2A protein. |
| Concentration | 1.0 mg/ml |
| General Readings |
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| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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| Specificity |
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Accessory Products
Recommended Secondary Antibodies for Epstein Barr Virus / EBV (11 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1371AP |
Rat IgG (H+L chain) antibody |
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|
Rabbit | AP | |||||
| OriGene Technologies GmbH | |||||||
| R1371B |
Rat IgG (H+L chain) antibody |
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|
Rabbit | Biotin | |||||
| OriGene Technologies GmbH | |||||||
| R1371F |
Rat IgG (H+L chain) antibody |
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|
Rabbit | FITC | |||||
| OriGene Technologies GmbH | |||||||
| R1371HRP |
Rat IgG (H+L chain) antibody |
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|
Rabbit | HRP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1371T |
Rat IgG (H+L chain) antibody |
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|
Rabbit | TRITC | |||||
| OriGene Technologies GmbH | |||||||
| R1413R |
Rat IgG (H+L chain), F(ab)2 Fragment antibody |
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|
Goat | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1415R |
Rat IgG F(ab)2 specific (adsorbed F(ab)2 Fragment) antibody |
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|
Goat | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1428R |
Rat IgG (H+L chain) F(ab')2 Fragment antibody |
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|
Donkey | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1439C2 |
Rat IgG (H+L chain, adsorbed) antibody |
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|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1439C3 |
Rat IgG (H+L chain, adsorbed) antibody |
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|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1439C5 |
Rat IgG (H+L chain, adsorbed) antibody |
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|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
