BP1002HRP Borrelia burgdorferi antibody

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1 ml / €500.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Borrelia burgdorferi

BP1002HRP

Product Description for Borrelia burgdorferi

Rabbit anti Borrelia burgdorferi.
Presentation: HRP
Product is tested for Western blot / Immunoblot, Paraffin Sections, Immunocytochemistry/Immunofluorescence, Enzyme Immunoassay.

Properties for Borrelia burgdorferi

Product Category Primary Antibodies
Quantity 1 ml
Presentation HRP
Applications E, ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Whole cell preparation from B. burgdorferi.
Application Western blot. 
Immunocytochemistry.
Immunohistochemistry on Formalin-Fixed Paraffin Sections.
Background Borrelia burgdorferi is a spirochete and the cause of Lyme disease, a tick transmitted illness of humans and animals. B. burgdorferi may persist in humans and animals for months or years following initial infection, despite a robust humoral immune response.
B. burgdorferi resembles other spirochetes in that it is a highly specialized, motile, two-membrane, spiral shaped bacteria which lives primarily as an extracellular pathogen. B. burgdorferi has an unusual genome compared with other eubacteria which includes a linear chromosome approximately one megabase in size and numerous linear and circular plasmids.
Caution Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
Concentration 1-2 mg/ml (OD280 nm, E0.1% = 1.4)
Product Citations
Purchased from Acris:
Unconjugated antibody is cited in:
  1. Eisendle K, Grabner T, Kutzner H, Zelger B. Possible role of Borrelia burgdorferi sensu lato infection in lichen sclerosus. Arch Dermatol. 2008 May;144(5):591-8. doi: 10.1001/archderm.144.5.591. PubMed PMID: 18490585.
General Readings
  1. Marques AR, Hornung RL, Dally L, Philipp MT. Detection of immune complexes is not independent of detection of antibodies in Lyme disease patients and does not confirm active infection with Borrelia burgdorferi. Clin Diagn Lab Immunol. 2005 Sep;12(9):1036-40. PubMed PMID: 16148168. (Free PMC Article available)
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Label:
Highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed
HRP
Molar radio:
Estimated molar HRP: IgG substitution is 2-3.
Buffer System:
PBS
Preservatives:
0.002% Thimerosal
Stabilizers:
10 mg/ml BSA
State:
Liquid purified Ig fraction
Specificity
Specificity:
Reactive Western blot bands at 83 kD, 41 kD, 34 kD, 31 kD and additional low MW bands.
Cross-reacts with Treponema pallidum, B. hermsii and B. parkerii.

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