IAP2 / BIRC2

Product Description for IAP2 / BIRC2

Rabbit anti Human, Mouse, Rat IAP2 / BIRC2.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Product Category	Primary Antibodies
Quantity	0.1 mg
Synonyms	API1, Baculoviral IAP repeat-containing protein 2, C-IAP1, HIAP-2, HIAP2, IAP homolog B, Inhibitor of apoptosis protein 2, MIHB, RING finger protein 48, RNF48, TNFR2-TRAF-signaling complex protein 2, cIAP1
Presentation	Aff - Purified
Reactivity	Hu, Ms, Rt
Applications	WB
Clonality	Polyclonal
Host	Rabbit
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Polyclonal Antibodies (de)

Immunogen	Swiss Prot Num: Q13490 Immunogen: Synthetic peptide surrounding amino acid 530 of human cIAP-1 GeneID: 329
Application	Western Blot: 0.5-4 μg/ml. Immunohistochemistry: 5 µg/ml. Jurkat cell lysate and Rat kidney tissue lysate can be used as positive controls.
Background	Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and -7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms.
Concentration	0.2 mg/ml
Storage	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	Purification: Affinity Chromatography Buffer System: PBS, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal State: Liquid purified Ig fraction Aff - Purified
Specificity	Specificity: This antibody detects cIAP-1. Species: Human, Mouse, Rat.
Gene ID	329

Catalog No.	Species	Pres.	Purity	Source
TP305373	IAP2 / BIRC2
	Human		> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.	HEK293 cells	20 µg / €748.00
					OriGene Technologies, Inc.
H00000329-P01-10	IAP2 / BIRC2
	Human	Purified	12.5% SDS-PAGE Stained with Coomassie Blue.
					Abnova Taiwan Corp.
H00000329-P01-25	IAP2 / BIRC2
	Human	Purified	12.5% SDS-PAGE Stained with Coomassie Blue.
					Abnova Taiwan Corp.

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