Caspase-9

Product Description for Caspase-9

Rabbit anti Mouse, Rat Caspase-9.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Product Category	Primary Antibodies
Quantity	0.1 mg
Synonyms	APAF-3, APAF3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, ICE-LAP6, ICE-like apoptotic protease 6, MCH6
Presentation	Aff - Purified
Reactivity	Ms, Rt
Applications	WB
Clonality	Polyclonal
Host	Rabbit
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Polyclonal Antibodies (de)

Immunogen	Swiss Prot Num: P55211 Immunogen: Synthetic peptide surrounding amino acid 345 of Mouse Caspase-9 GeneID: 842
Application	Western Blot: 0.5-4.0 µg/ml. Mouse small intestine and rat kidney tissue lysates can be used as Positive Controls.
Background	Caspase-9 is one of the most important caspases among the caspase family members. Upon induction of apoptosis, cytochrome c released from mitochondria associates with procaspase- 9/Apaf-1. The complex processes procaspase-9 into a large subunit (35 kDa or 17 kDa) and small (10 kDa) by self-cleavage at D315. Activated caspase-9 further cleaves other caspase members including caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. In addition to self-cleavage, procaspase-9 can also be cleaved in vivo by caspase-3 at D330. The process served as a positive feedback to amplify the apoptotic signal in caspase activation pathway.
Concentration	0.2 mg/ml
Storage	Store the antibody undiluted at -20°C or (in aliquots) at -70°C for long term storage. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	Purification: Protein A Chromatography. Buffer System: PBS, pH 7.2, containing 30% Glycerol, 0.5% BSA and 0.01% Thimerosal. State: Liquid purified Ig fraction. Aff - Purified
Specificity	Specificity: The antibody detects 45 kDa procaspase-9, 35/37 kDa cleaved large fragment and the 25 kDa fully cleaved Caspase-9. Species: Mouse and Rat.
Gene ID	842

Catalog No.	Species	Purity	Source
TP313375	Caspase-9 (transcript variant beta)
	Human	> 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.	HEK293 cells	20 µg / €748.00
				OriGene Technologies, Inc.
H00000842-P01-10	Caspase-9
	Human	12.5% SDS-PAGE Stained with Coomassie Blue.	in vitro transl.
				Abnova Taiwan Corp.
H00000842-P01-25	Caspase-9
	Human	12.5% SDS-PAGE Stained with Coomassie Blue.	in vitro transl.
				Abnova Taiwan Corp.
P1284	Caspase-9
	Human
				Abnova Taiwan Corp.
P4040	Caspase-9
	Human
				Abnova Taiwan Corp.

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