Switch to Europe/Worldwide website Switch to German website Switch to French website Switch to OriGene Technologies, Inc. (North America)
Home » Cytokeratin 10

BM2298P Cytokeratin 10 antibody

See related secondary antibodies

Search for all "Cytokeratin 10"

0.1 mg / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

View Datasheet

Highly validated antibody!

Quick Overview

Mouse anti Canine, Human, Mouse, Porcine, Rat, Zebrafish Cytokeratin 10 RKSE60

BM2298P

More Views

  • BM2298P
  • BM2298P
  • BM2298P

Product Description for Cytokeratin 10

Mouse anti Canine, Human, Mouse, Porcine, Rat, Zebrafish Cytokeratin 10 RKSE60.
Presentation: Purified
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Flow Cytometry.

Properties for Cytokeratin 10

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms CK-10, CK10, Cytokeratin-10, K10, KPP, KRT10, Keratin, Keratin-10, Type I Cytoskeletal 10
Presentation Purified
Reactivity Can, Hu, Ms, Por, Rt, Ze
Applications C, F, ICC/IF, WB
Clonality Monoclonal
Clone RKSE60
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P13645
Immunogen:
Cytokeratins from the Human epidermis
GeneID:
3858
Isotype control AM03095PU-N, SM10P (for use in human samples), SM20P (for use in rat samples)
Application Immunoblotting: 1/100-1/1000.
Flow Cytometry: 1/100-1/200.
Immunocytochemistry.
Immunohistochemistry on Frozen Sections: 1/100-1/200 (with Avidin-Biotinylated Horseradish peroxidase complex (ABC) as detection reagent).
Background Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
Concentration 1.0 mg/ml
General Readings
  1. Ramaekers FC, Puts JJ, Moesker O, Kant A, Huysmans A, Haag D, et al. Antibodies to intermediate filament proteins in the immunohistochemical identification of human tumours: an overview. Histochem J. 1983 Jul;15(7):691-713. PubMed PMID: 6350235.
  2. Puts JJ, Moesker O, Kenemans P, Vooijs GP, Ramaekers FC. Expression of cytokeratins in early neoplastic epithelial lesions of the uterine cervix. Int J Gynecol Pathol. 1985;4(4):300-13. PubMed PMID: 2417968.
  3. Broers JL, Carney DN, Klein Rot M, Schaart G, Lane EB, Vooijs GP, et al. Intermediate filament proteins in classic and variant types of small cell lung carcinoma cell lines: a biochemical and immunochemical analysis using a panel of monoclonal and polyclonal antibodies. J Cell Sci. 1986 Jul;83:37-60. PubMed PMID: 2433295.
  4. Ramaekers F, Huysmans A, Schaart G, Moesker O, Vooijs P. Tissue distribution of keratin 7 as monitored by a monoclonal antibody. Exp Cell Res. 1987 May;170(1):235-49. PubMed PMID: 2436934.
  5. Van Muijen GN, Warnaar SO, Ponec M. Differentiation-related changes of cytokeratin expression in cultured keratinocytes and in fetal, newborn, and adult epidermis. Exp Cell Res. 1987 Aug;171(2):331-45. PubMed PMID: 2442018.
  6. Bijman JT, Wagener DJ, van Rennes H, Wessels JM, Ramaekers FC, van den Broek P. Modulation of placental alkaline phosphatase activity and cytokeratins in human HN-1 cells by butyrate, retinoic acid, catecholamines and histamine. Br J Cancer. 1987 Aug;56(2):127-32. PubMed PMID: 2444242. (Free PMC Article available)
  7. van Erp PE, Rijzewijk JJ, Boezeman JB, Leenders J, de Mare S, Schalkwijk J, et al. Flow cytometric analysis of epidermal subpopulations from normal and psoriatic skin using monoclonal antibodies against intermediate filaments. Am J Pathol. 1989 Nov;135(5):865-70. PubMed PMID: 2479273. (Free PMC Article available)
  8. Ramaekers F, van Niekerk C, Poels L, Schaafsma E, Huijsmans A, Robben H, et al. Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas. Am J Pathol. 1990 Mar;136(3):641-55. PubMed PMID: 1690512. (Free PMC Article available)
  9. Schaafsma HE, Ramaekers FC, van Muijen GN, Lane EB, Leigh IM, Robben H, et al. Distribution of cytokeratin polypeptides in human transitional cell carcinomas, with special emphasis on changing expression patterns during tumor progression. Am J Pathol. 1990 Feb;136(2):329-43. PubMed PMID: 1689541. (Free PMC Article available)
  10. Smedts F, Ramaekers F, Robben H, Pruszczynski M, van Muijen G, Lane B, et al. Changing patterns of keratin expression during progression of cervical intraepithelial neoplasia. Am J Pathol. 1990 Mar;136(3):657-68. PubMed PMID: 1690513. (Free PMC Article available)
  11. Franssen, M.E.J., Boezeman, J.B.M., van de Kerkhof, P.C.M. and van Erp, P.E.J. (2003). Monitoring hyperproliferative disorders in human skin: flow cytometry of changing cytokeratin expression, Cytometry Part B (Clinical Cytometry) 57B, 32-39.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freeze-thaw cycles.
Shelf life: One year from despatch.
Format
Buffer System:
PBS containing 0.09% Sodium Azide as preservative.
State:
Liquid purified IgG fraction
Purified
Species Reactivity
Species reactivity (tested):
Canine, Human, Mouse, Rat, Swine, Zebrafish.
Specificity
Specificity:
RKSE60 reacts exclusively with Cytokeratin 10 which is present in keratinizing stratified epithelia and in differentiated areas of highly differentiated squamous cell carcinomas.
Gene ID 3858

Accessory Products

Proteins and/or Positive Controls

Proteins for Cytokeratin 10 (6 products)

Catalog No. Species Pres. Purity   Source  

Cytokeratin 10
Cytokeratin 10 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Cytokeratin 10
Cytokeratin 10 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Cytokeratin 10
Cytokeratin 10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Cytokeratin 10
Cytokeratin 10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Cytokeratin 10
Cytokeratin 10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Cytokeratin 10
Cytokeratin 10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Recommended Secondary Antibodies for Cytokeratin 10 (11 products)

Catalog No. Host Clone/Iso. Pres.   React. Applications  

Mouse IgG (H+L chain) antibody
Mouse IgG (H+L chain) antibody Rabbit AP C, E, WB
    OriGene Technologies GmbH

Mouse IgG (H+L chain) antibody
Mouse IgG (H+L chain) antibody Rabbit Biotin C, E, WB
    OriGene Technologies GmbH

Mouse IgG (H+L chain) antibody
Mouse IgG (H+L chain) antibody Rabbit FITC E, ICC/IF
    OriGene Technologies GmbH

Mouse IgG (H+L chain) antibody
Mouse IgG (H+L chain) antibody Rabbit HRP C, E, WB
    OriGene Technologies GmbH

Mouse IgG (H+L chain) antibody
Mouse IgG (H+L chain) antibody Rabbit Texas Red ICC/IF
    OriGene Technologies GmbH

Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody Rabbit PE F
    OriGene Technologies GmbH

Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody Goat PE
    OriGene Technologies GmbH

Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody Donkey PE
    OriGene Technologies GmbH

Mouse IgG (H+L chain), adsorbed antibody
Mouse IgG (H+L chain), adsorbed antibody Goat Cy2
    OriGene Technologies GmbH

Mouse IgG (H+L chain), adsorbed antibody
Mouse IgG (H+L chain), adsorbed antibody Goat Cy3
    OriGene Technologies GmbH

Mouse IgG (H+L chain), adsorbed antibody
Mouse IgG (H+L chain), adsorbed antibody Goat Cy5
    OriGene Technologies GmbH
Click here to see all secondary antibodies for Cytokeratin 10
Compare Products

You have no items to compare.

My Cart

You have no items in your shopping cart.

Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
© Copyright 1998 - 2018 OriGene Technologies GmbH
  • LinkedIn