HMGB1 (1-215, His-tag) - AR03001PU-S

Product Description for HMGB1

HMGB1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	Amphoterin, HMG-1, HMG1, HMGB-1, High mobility group protein 1, High mobility group protein B1
Presentation	Purified
Molecular weight	25 kDa
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P09429
Purity	> 90 % pure by SDS-PAGE.
Add. information	NCBI Accession No.: NP_002119
Background	High mobility group box1 protein (HMGB1) is a very abundant chromatin-binding protein residing in the eukaryotic cell nucleus and acting in the assembly of nucleoprotein complexes. Inside the cell, HMGB1 binds to DNA and has a role in transcriptional regulation. Outside the cell, HMGB1 acts as a cytokine and has activities that resemble those of tumor necrosis factor.
Concentration	1.0 mg/ml
General Readings	Palumbo R J., et al. (2004) Cell Biol. Feb 2; 164(3): Andersson U., et al (2002) Leukoc Biol. Dec; 72(6):1084-91
Storage	Store the antibody undiluted at 2-8°C for 2 weeks or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Source	High Five insect cells
Description	Description: Recombinant human HMGB1 (aa. 1-215) His-tagged. AA Sequence: `MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEE EDEEDEDEEE DDDDELEHHH HHH` Molecular weight: (223 aa)
Format	Buffer System: 20 mM Tris pH 8.0, 1 mM EDTA, 0.5 mM DTT, 10% Glycerol. Endotoxin level: < 1.0 EU per 1 µg of protein (determined by LAL method) Purity: >90% pure by SDS-PAGE. State: Liquid purified by conventional Chromatography techniques. Purified