DIABLO / SMAC (56-239) - AR03005PU-N

Product Description for DIABLO / SMAC

DIABLO / SMAC.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	Diablo homolog mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase
Presentation	Purified
Molecular weight	22 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9NR28
Purity	> 95 % > 95 % by SDS PAGE
Add. information	NCBI Accession No: NP_063940
Background	Smac/Diablo is one of the proapoptotic proteins. Smac promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding to inhibitor of apoptosis proteins (IAPs) and removing their inhibitory activity.
Concentration	1.0 mg/ml
General Readings	Srinivasula SM., et al. (2000). J Biol Chem. 275(46):36152-7. DU C., et al. (2000). Cell. 102(1):33-42.
Storage	Store at -20°C. Avoid repeated freezing and thawing. Shelf life: six months from despatch.
Source	E. coli
Description	Description: Recombinant human Smac fused to T7-tag. AA Sequence: `MASMTGGQQM GRGSMAVPIA QKSEPHSLSS EALMRRAVSL VTDSTSTFLS QTTYALIEAI TEYTKAVYTL TSLYRQYTSL LGKMNSEEED EVWQVIIGAR AEMTSKHQEY LKLETTWMTA VGLSEMAAEA AYQTGADQAS ITARNHIQLV KLQVEEVHQL SRKAETKLAE AQIEELRQKT QEEGEERAES EQEAYLRED` Molecular weight: 22 kDa (199 aa)
Format	Buffer System: 20mM Tris pH 7.5 Purity: >95% > 95 % by SDS PAGE State: Liquid protein, purified by conventional chromatography techniques Purified