BIRC7 / LIVIN (1-298) - AR03006PU-L

Product Description for BIRC7 / LIVIN

BIRC7 / LIVIN.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	Baculoviral IAP repeat-containing protein 7, KIAP, Kidney inhibitor of apoptosis protein, Livin, MLIAP, Melanoma inhibitor of apoptosis protein, RING finger protein 50, RNF50
Presentation	Purified
Molecular weight	34 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q96CA5
Purity	> 90 % > 90 % by SDS PAGE
Add. information	NCBI Accession No.: NP_647478
Background	Livin is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING zinc finger (RZF) domain. Livin has direct interaction with several caspases including caspase-3, -7, and -9. This protein inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP.
Concentration	1.0 mg/ml
General Readings	Kasof GM, et al. (2001). J Biol Chem. 2; 276(5):3238-46. Ashhab Y, et al. (2001). FEBS Lett. 20; 495(1-2):56-60.
Storage	Store at -20 °C. Avoid repeated freezing and thawing. Shelf life: six months from despatch.
Source	E. coli
Description	Description: Recombinant human Livin fused to His-tag at N-terminus AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGPKDSAKCL HRGPQPSHWA AGDGPTQERC GPRSLGSPVL GLDTCRAWDH VDGQILGQLR PLTEEEEEEG AGATLSRGPA FPGMGSEELR LASFYDWPLT AEVPPELLAA AGFFHTGHQD KVRCFFCYGG LQSWKRGDDP WTEHAKWFPS CQFLLRSKGR DFVHSVQETH SQLLGSWDPW EEPEDAAPVA PSVPASGYPE LPTPRREVQS ESAQEPGGVS PAEAQRAWWV LEPPGARDVE AQLRRLQEER TCKVCLDRAV SIVFVPCGHL VCAECAPGLQ LCPICRAPVR SRVRTFLS` Molecular weight: 34kDa (318 aa)
Format	Buffer System: 20mM Tris pH 8.0, 1mM DTT, 0.1M NaCl, 2mM EDTA, 20% glycerol Purity: >90% > 90 % by SDS PAGE State: Liquid protein, purified by conventional chromatography techniques Purified