AM00684PU-N Cortisol antibody

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1 mg / €520.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Cortisol CORT-2

AM00684PU-N

Product Description for Cortisol

Mouse anti Cortisol CORT-2.
Presentation: Purified
Product is tested for Enzyme Immunoassay.

Properties for Cortisol

Product Category Primary Antibodies
Quantity 1 mg
Synonyms Hydrocortisone
Presentation Purified
Applications E
Clonality Monoclonal
Clone CORT-2
Host Mouse
Isotype IgG3
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Cortisol-3 (CMO) -BSA.
Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Remarks:
Source: Ascites.
Isotype control AM03097PU-N
Application Can be used in competitive assay of Cortisol.
Background Cortisol is the most potent glucocorticoid produced by the human adrenal.
It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
Concentration 5.0 mg/ml (OD280nm, E0.1% = 1.4)
Storage Store the antibody undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Purification:
Protein G Chromatography.
Buffer System:
PBS, pH 7.4 containing 0.09% Sodium Azide as preservative
State:
Liquid purified IgG fraction (>95% pure).
Purified
Specificity
Specificity:
This antibody recognizes Cortisol-BSA conjugate and free Cortisol.
There is no cross-reactivity with BSA.
Cross-reactivity: (50% displacement of cortisol-3-125-Iodine)
Cortisol: 100%
Corticosterone: 49%
17-Hydroxyprogesterone: 0%

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