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BM5090 LCMV antibody

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5 ml / €240.00
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Quick Overview

Mouse anti Human, Mouse LCMV M 104

BM5090

Product Description for LCMV

Mouse anti Human, Mouse LCMV M 104.
Presentation: Supernatant
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for LCMV

Product Category Primary Antibodies
Quantity 5 ml
Synonyms Lymphocytic choriomeningitis virus
Presentation Supernatant
Reactivity Hu, Ms
Applications C, ICC/IF, WB
Clonality Monoclonal
Clone M 104
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
LCMV isolated from Human HeLa Cells.
Application Immunoblotting (Western).
Immunohistochemistry on Frozen Tissue.
Immunofluorescence Microscopy (Ready-to-Use).
Background Lymphocytic choriomeningitis virus (LCMV), the first member of the Arena-virus family to be isolated, is the causative agent of a zoonosis acquired from chronically viremic mice or hamsters. LCMV primarily infects wild mice and it is estimated that 5% of all wild mice carry LCMV. Mice can asymptomatically carry and shed the virus in saliva, urine and faeces. People and other animals become infected through contact with these secretions or by inhalation of dried particles from them. The clinical spectrum of acquired human LCMV infection ranges from inapparent and asymptomatic to, in rare instances, severely symptomatic, systemic, and fatal central nervous system (CNS) disease. Intrauterine LCMV infection has resulted in fetal or neonatal death, as well as hydrocephalus and chorioretinitis in infants. The virus is usually only dangerous to those who are immunocompromised.
General Readings
  1. Doherty PC, Ceredig R, Allan JE. Immunogenetic analysis of cellular interactions governing the recruitment of T lymphocytes and monocytes in lymphocytic choriomeningitis virus-induced immunopathology. Clin Immunol Immunopathol. 1988 Apr;47(1):19-26. PubMed PMID: 3258209.
  2. Salvato M, Shimomaye E, Oldstone MB. The primary structure of the lymphocytic choriomeningitis virus L gene encodes a putative RNA polymerase. Virology. 1989 Apr;169(2):377-84. PubMed PMID: 2705303.
  3. Childs JE, Glass GE, Korch GW, Ksiazek TG, Leduc JW. Lymphocytic choriomeningitis virus infection and house mouse (Mus musculus) distribution in urban Baltimore. Am J Trop Med Hyg. 1992 Jul;47(1):27-34. PubMed PMID: 1636880.
  4. Roebroek RM, Postma BH, Dijkstra UJ. Aseptic meningitis caused by the lymphocytic choriomeningitis virus. Clin Neurol Neurosurg. 1994 May;96(2):178-80. PubMed PMID: 7924087.
  5. Barton LL, Hyndman NJ. Lymphocytic choriomeningitis virus: reemerging central nervous system pathogen. Pediatrics. 2000 Mar;105(3):E35. PubMed PMID: 10699137.
  6. Lee KJ, Novella IS, Teng MN, Oldstone MB, de La Torre JC. NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs. J Virol. 2000 Apr;74(8):3470-7. PubMed PMID: 10729120. (Free PMC Article available, 5 images available)
  7. Cornu TI, de la Torre JC. RING finger Z protein of lymphocytic choriomeningitis virus (LCMV) inhibits transcription and RNA replication of an LCMV S-segment minigenome. J Virol. 2001 Oct;75(19):9415-26. PubMed PMID: 11533204. (Free PMC Article available, 9 images available)
  8. Sánchez AB, de la Torre JC. Genetic and biochemical evidence for an oligomeric structure of the functional L polymerase of the prototypic arenavirus lymphocytic choriomeningitis virus. J Virol. 2005 Jun;79(11):7262-8. PubMed PMID: 15890965. (Free PMC Article available, 4 images available)
  9. Hoey J. Lymphocytic choriomeningitis virus. CMAJ. 2005 Oct 25;173(9):1033. PubMed PMID: 16247097. (Free PMC Article available, 3 images available)
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Preservatives:
0.09% Sodium Azide
State:
Liquid Hybridoma Culture Supernatant
Supernatant
Species Reactivity
Species reactivity (tested):
Human and Mouse.
Specificity
Specificity:
Reacts with LCMV-infected cells (e.g. Vero, HeLa). 
This LCMV Antibody (Clone M104) is recommended for detection of LCMV infected cells (e.g. Vero, HeLa) of LCMV origin.

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Click here to see all secondary antibodies for LCMV
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