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BM5547 Mucin-5AC antibody

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1 ml / €360.00
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Quick Overview

Mouse anti Chicken, Feline, Human, Mammalia, Monkey, Mouse, Porcine, Rabbit, Rat Mucin-5AC 45 MI

BM5547

Product Description for Mucin-5AC

Mouse anti Chicken, Feline, Human, Mammalia, Monkey, Mouse, Porcine, Rabbit, Rat Mucin-5AC 45 MI.
Presentation: Supernatant
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Paraffin Sections.

Properties for Mucin-5AC

Product Category Primary Antibodies
Quantity 1 ml
Synonyms Gastric mucin, LeB, Lewis B blood group antigen, MUC5, MUC5AC, Major airway glycoprotein, Mucin-5 subtype AC, TBM, Tracheobronchial mucin, tracheobronchial
Presentation Supernatant
Reactivity Chk, Fe, Hu, Mam, Mky, Ms, Por, Rb, Rt
Applications C, ICC/IF, P
Clonality Monoclonal
Clone 45 MI
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P98088
Immunogen:
Mucin isolated from ovarian mucinous cysts and colonic mucosa.
Application Immunofluorescence Microscopy.
Immunohistochemistry of Frozen and Paraffin Sections (with ethanol fixed tissue): 1/10–1/40. 
with PFA fixation protease treatment is recommended
Positive Control: Gastric mucosa of stomach.
Background Mucin is an important tumor-associated marker for adenocarcinomas.
Product Citations
Purchased from Acris:
  1. Goris K, Uhlenbruck S, Schwegmann-Wessels C, Köhl W, Niedorf F, Stern M, et al. Differential sensitivity of differentiated epithelial cells to respiratory viruses reveals different viral strategies of host infection. J Virol. 2009 Feb;83(4):1962-8. doi: 10.1128/JVI.01271-08. Epub 2008 Dec 3. PubMed PMID: 19052091. (Free PMC Article available, 6 images available)
  2. Huang D, Xu B, Yang X, Xu B, Zhao J. Conjunctival structural and functional reconstruction using acellular bovine pericardium graft (Normal GEN®) in rabbits. Graefes Arch Clin Exp Ophthalmol. 2016 Apr;254(4):773-83. doi: 10.1007/s00417-015-3201-1. Epub 2015 Dec 1. PubMed PMID: 26626771.
General Readings
  1. Bara J, Decaens C, Loridon-Rosa B, Oriol R. Immunohistological characterization of mucin epitopes by pre-treatment of gastro-intestinal sections with periodic acid. J Immunol Methods. 1992 Apr 27;149(1):105-13. PubMed PMID: 1374774.
  2. Bara J, Gautier R, Mouradian P, Decaens C, Daher N. Oncofetal mucin M1 epitope family: characterization and expression during colonic carcinogenesis. Int J Cancer. 1991 Jan 21;47(2):304-10. PubMed PMID: 1988372.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
PBS
Preservatives:
0.09% Sodium Azide
Stabilizers:
1% BSA
State:
Liquid Culture Supernatant
Supernatant
Species Reactivity
Species reactivity (tested):
Human, most mammals (including Monkey, Cat, Pig, Rat, Mouse, Rabbit, Hedgehog), Chicken.Negative on cow.
Specificity
Specificity:
The antibody is reactive with the peptide core of gastric mucin (MUC5AC, earlier also described as mucin M1). Mucin is an important tumor-associated marker for adenocarcinomas. The antibody shows specificity to gastric mucosa, but is also reactive with stomach and colon carcinomas. Most breast carcinomas are negative. The antigen is localized in the cytoplasm.

Accessory Products

Proteins and/or Positive Controls

Proteins for Mucin-5AC (2 products)

Catalog No. Species Pres. Purity   Source  

Mucin-5AC
Mucin-5AC Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Mucin-5AC
Mucin-5AC Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

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