discontinued

BP492 Gelsolin antibody

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Quick Overview

Sheep anti Bovine, Human, Mouse, Porcine Gelsolin

BP492

Product Description for Gelsolin

Sheep anti Bovine, Human, Mouse, Porcine Gelsolin.
Presentation: Purified
Product is tested for Enzyme Immunoassay.

Properties for Gelsolin

Product Category Primary Antibodies
Quantity 1 ml
Synonyms AGEL, Actin-depolymerizing factor, Brevin, GSN
Presentation Purified
Reactivity Bov, Hu, Ms, Por
Applications E
Clonality Polyclonal
Host Sheep
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P06396
Immunogen:
Gelsolin - conjugated with KLH.
The C-terminal human sequence (aa 729-742: F-V-G-W-F-L-G-W-D-D-D-Y-W-S) used to make this antibody is in an area common to the plasma and cytoplasmic form of the molecule.
GeneID:
2934
Application ELISA: 1/60 - 1/640 in a simple ELISA using 1 μg of peptide antigen coated per well, with AP conjugated anti-sheep for detection.
Use the same dilutions with bovine plasma Gelsolin.
Background Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin, which appears to account for the difference in relative molecular weights.
Concentration 46.0 mg/ml (by OD 280 nm)
Storage Aliquot and store the antibody at -20°C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Ammonium sulphate fractionation
Buffer System:
PBS buffer, pH 7.2, containing 0.09% sodium azide
State:
Liquid Ig fraction
Purified
Specificity
Specificity:
Human gelsolin (plasma + cytoplasmic).
Reactive with native bovine plasma gelsolin in simple ELISA.
Mouse and pig gelsolin also have a high degree of homology with the area used for immunization.
Gene ID 2934

Accessory Products

Proteins and/or Positive Controls

Proteins for Gelsolin (6 products)

Catalog No. Species Pres. Purity   Source  

Gelsolin (transcript variant 1)

Gelsolin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

Gelsolin

Gelsolin Bovine Purified SDS PAGE: >95%
  OriGene Technologies GmbH

Gelsolin

Gelsolin Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Gelsolin

Gelsolin Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Gelsolin

Gelsolin Human 12.5% SDS-PAGE Stained with Coomassie Blue
  Abnova Taiwan Corp.

Gelsolin

Gelsolin Human 12.5% SDS-PAGE Stained with Coomassie Blue
  Abnova Taiwan Corp.

Positive controls for Gelsolin (2 products)

Catalog No. Species Pres. Purity   Source  

GSN 293T Cell Transient Overexpression Lysate(Denatured)

GSN 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

GSN overexpression lysate

GSN overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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