discontinued

SP1318P Interleukin-21 receptor / IL21R (20-32) antibody

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Rabbit anti Human, Mouse, Rat Interleukin-21 receptor / IL21R

Product Description for Interleukin-21 receptor / IL21R

Rabbit anti Human, Mouse, Rat Interleukin-21 receptor / IL21R.
Properties: (20-32)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Interleukin-21 receptor / IL21R

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms IL-21R, IL21 receptor, NILR, Novel interleukin receptor
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9HBE5
Immunogen:
Synthetic peptide corresponding to amino acids 20-32 of human IL-21 receptor.
AA Sequence:
CPDLVCYTDYLQT
GeneID:
50615
Property 20-32
Application Western Blot.
Background IL21 Receptor is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.
Concentration 0.5 mg/ml
General Readings
  1. Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature. 2000 Nov 2;408(6808):57-63. PubMed PMID: 11081504.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography
Buffer System:
PBS containing 0.02% Sodium Azide
State:
Liquid purified IgG
Aff - Purified
Specificity
Specificity:
This antibody recognises an epitope within the N-terminal region of interleukin -21 receptor. The antibody detects a band of approximately 60kD in western blot analysis of human raji cells.
Species:
Human.

Accessory Products

Proteins and/or Positive Controls

Proteins for Interleukin-21 receptor / IL21R (4 products)

Catalog No. Species Pres. Purity   Source  

Interleukin-21 receptor / IL21R (transcript variant 2)

Interleukin-21 receptor / IL21R Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
50 µg / €299.00
  OriGene Technologies, Inc.

Interleukin-21 receptor / IL21R

Interleukin-21 receptor / IL21R Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Interleukin-21 receptor / IL21R

Interleukin-21 receptor / IL21R Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Interleukin-21 receptor / IL21R

Interleukin-21 receptor / IL21R Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for Interleukin-21 receptor / IL21R (3 products)

Catalog No. Species Pres. Purity   Source  

IL21R overexpression lysate

IL21R overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

IL21R overexpression lysate

IL21R overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.

IL21R overexpression lysate

IL21R overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.
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