AR03023PU-L Heat shock protein 65 / HSP65 (native)

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2x0.1 mg / €740.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Heat shock protein 65 / HSP65

AR03023PU-L

Product Description for Heat shock protein 65 / HSP65

Heat shock protein 65 / HSP65.
Presentation: Aff - Purified

Properties for Heat shock protein 65 / HSP65

Product Category Proteins & Growth Factors
Quantity 2x0.1 mg
Synonyms 60 kDa chaperonin 2, Antigen A, Cell wall protein A, MT0456, MTV037.04, Protein Cpn60-2, Rv0440, groEL protein 2, groEL-2, groEL2, groL2, hsp65
Presentation Aff - Purified
Source E. coli
Species (Protein) Mycobacteria
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P0A520
Purity > 90 % > 90 % pure as determined by SDS-PAGE analysis
Application WB control.
Background Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65.
The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
Concentration 1.0 mg/ml
General Readings
  1. Thole J.E.R., et al. (1985) Infect. Immuno. 50: 800-806.
  2. Thole J.E.R., et al., (1987) Infect. Immuno. 55: 1466-1475.
  3. Koll H., et al. (1992) Cell 68: 1163-1175.
  4. Shinnick T.M. Sweetser D., Thole J., van Embden J. and Young R.A. (1987) Infect. Immuno. 55: 1932-1935.
  5. Van Eden, W., et al. (1988) Nature 331: 171-178.
  6. Cobelens P.M., et al. (2002) Rheumatology 41: 775-779.
Storage Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Source E. coli
Description
Description:
Recombinant Hsp65 Protein from Mycobacterium bovis BCG, native sequence
Format
Buffer System:
PBS (pH 7.0), 0.09% sodium azide, and 50% glycerol.
Purity:
>90% > 90 % pure as determined by SDS-PAGE analysis
State:
Liquid , affinity purified protein
Aff - Purified
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