Amiloride-sensitive cation channel 3 Lysate - NBL1-07232

Product Description for Amiloride-sensitive cation channel 3 Lysate

Product is tested for Western blot / Immunoblot.

Immunogen	Swiss Prot Num: Q9UHC3
Add. information	This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes.
Application	Western Blot, This product is intended for use as a positive control in Western Blot., Western Blot
Background	This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium. Alternative splicing of this gene generates three transcript variants encoding distinct isoforms. [provided by RefSeq]. Transcript Variant: This variant (1) uses an alternate splice site in the 3' coding region, compared to variant 2. This results in a frameshift and distinct C-terminus in isoform a, compared to isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Concentration	1 mg/ml
Storage	Store at -20C. Avoid freeze-thaw cycles.