Product Description for HTLV1 p24 core
HTLV1 p24 core.
Presentation: Purified
Presentation: Purified
Properties for HTLV1 p24 core
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 1 mg |
| Presentation | Purified |
| Source | E. coli |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Purity | >95.0% pure (As determined by HPLC-C4, and 10.0% PAGE). Purification Method: Organic extraction S-300> HPLC. |
|---|---|
| Application | Antigen in ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems. |
| Background | Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies). |
| Concentration | 1.0 mg/ml |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
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