Product Description for Resistin / RETN
Presentation: Purified
Properties for Resistin / RETN
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 25 µg |
| Synonyms | ADSF, Adipose tissue-specific secretory factor, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, FIZZ3, HXCP1, RSTN |
| Presentation | Purified |
| Molecular weight | 20.0 kDa |
| Source | E. coli |
| Species (Protein) | Rat |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 97 % pure by SDS-PAGE gel and HPLC analyses |
| Add. information | Centrifuge vial before opening. |
| Background | Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin’s ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. |
| Storage | Prior to reconstitution store at 2-8°C. |
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