17-beta-HSD2 / HSD17B2 antibody
Principal name
17-beta-HSD2 / HSD17B2 antibody
Alternative names for 17-beta-HSD2 / HSD17B2 antibody
Testosterone 17-beta-dehydrogenase, 20-alpha HSD, E2DH, EDH17B2, Estradiol 17-beta-dehydrogenase 2, Microsomal 17-beta-hydroxysteroid dehydrogenase
Ncbi ID
NP_002144, 9606, NP_002144.1, NM_002153, NP_032316.2, NM_024391
Available reactivities
Available hosts
Available applications
ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Flow Cytometry (F)
Background of 17-beta-HSD2 / HSD17B2 antibody
HSD17B2(17-BETA-HYDROXYSTEROID DEHYDROGENASE II), also called 17-BETA-HSD II, is an anzyme which have 387 amino acids with a predicted molecular weight of 42,782 and associate with the membranes of the endoplasmic reticulum. Its Cytogenetic location is 16q23.3. The type 2 enzyme was capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. HSD17B2 mRNA was detected in 18 of 42 (43%) adenomas but not in prolactinomas. In the human endometrium, inactivation of 17-beta-estradiol to estrone is catalyzed by HSD17B2.And HSD17B2 activity distinguishing between disease-free and diseased endometria. HSD17B2 efficiently catalyzes the oxidative metabolism of androgens and estrogens, and it is expressed in a large series of human peripheral tissues. The previous paradigm that HSD17B2 activity in the endometrium is elevated during the secretory phase is confined to diseased endometrium but not to disease-free endometrium.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA332485 | 17-beta-HSD2 / HSD17B2 antibody |
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| Rabbit anti-HSD17B2 Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms |
0.1 mg /
€335.00
|
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| OriGene Technologies, Inc. | |||||||
 +1 additional image |
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| TA504565 | 17-beta-HSD2 / HSD17B2 antibody |
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| HSD17B2 mouse monoclonal antibody, clone OTI4F10 (formerly 4F10) | |||||||
 |
Mouse | IgG1 | OTI4F10 | Purified | Hu | F, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
| +2 additional images |
|
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| TA504616 | 17-beta-HSD2 / HSD17B2 antibody |
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| HSD17B2 mouse monoclonal antibody, clone OTI3E9 (formerly 3E9) | |||||||
 |
Mouse | IgG1 | OTI3E9 | Purified | Hu | F, WB |
0.1 ml /
€379.00
|
| OriGene Technologies, Inc. | |||||||
| +2 additional images |
|
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP303293 | 17-beta-HSD2 / HSD17B2 |
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| Recombinant protein of human hydroxysteroid (17-beta) dehydrogenase 2 (HSD17B2) | |||||
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Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY419500 | HSD17B2 overexpression lysate |
|
 |
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR208169L2V | Lenti ORF particles, Hsd17b2 (GFP-tagged ORF) - Rat hydroxysteroid (17-beta) dehydrogenase 2 (Hsd17b2), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| RR208169L1V | Lenti ORF particles, Hsd17b2 (Myc-DDK-tagged ORF) - Rat hydroxysteroid (17-beta) dehydrogenase 2 (Hsd17b2), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||