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ACD antibody

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Principal name

ACD antibody

Alternative names for ACD antibody

PIP1, PTOP, TINT1, TPP1, Adrenocortical dysplasia protein homolog

SwissProt ID

Q4FZR5 (Rat), Q5EE38 (Mouse), Q96AP0 (Human)

Gene ID

65057 (ACD), 497652 (Acd), 307798

Ncbi ID

9606, NP_001075955, NM_001012638, NP_001075955.1, NM_022914, NM_001082486, NM_001082487, NP_075065, NP_001012656.1, NM_001037193

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Flow Cytometry (F)

Background of ACD antibody

ACD is a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere.This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

General readings

"Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator." Keegan C.E., Hutz J.E., Else T., Adamska M., Shah S.P., Kent A.E., Howes J.M., Beamer W.G., Hammer G.D. Hum. Mol. Genet. 14:113-123(2005)

H00065057-M02 - ACD
Immunoperoxidase of monoclonal antibody to ACD on formalin-fixed paraffin-embedded human heart tissue. [antibody concentration 2ug/ml]
H00065057-M02 - ACD
Immunofluorescence of monoclonal antibody to ACD on HeLa cell. [antibody concentration 10 ug/ml]
H00065057-B01P - ACD
Western Blot analysis of ACD expression in transfected 293T cell line (H00065057-T01) by ACD MaxPab polyclonal antibody.Lane 1: ACD transfected lysate(59.84 KDa).Lane 2: Non-transfected lysate.
H00065057-B01P - ACD
ACD MaxPab polyclonal antibody. Western Blot analysis of ACD expression in HepG2.
H00065057-D01P - ACD
Western Blot analysis of ACD expression in transfected 293T cell line (H00065057-T02) by ACD MaxPab polyclonal antibody.Lane 1: ACD transfected lysate(57.70 KDa).Lane 2: Non-transfected lysate.
ARP58253_P050 - ACD
Human NCI-H226; WB Suggested Anti-ACD Antibody Titration: 0.2-1 ug/ml. Positive Control: NCI-H226 cell lysate; ACD antibody - middle region (ARP58253_P050) in Human NCI-H226 cells using Western Blot
ARP58254_P050 - ACD
Human Brain; WB Suggested Anti-ACD Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human brain; ACD antibody - C-terminal region (ARP58254_P050) in Human Brain cells using Western Blot
ARP36813_P050 - ACD
Mouse Muscle; WB Suggested Anti-Acd Antibody Titration: 0.2-1 ug/ml. Positive Control: Mouse Muscle; Acd antibody - C-terminal region (ARP36813_P050) in Mouse Muscle cells using Western Blot
TA504201 - ACD
Anti-ACD mouse monoclonal antibody (TA504201) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD(RC204381).
TA504201 - ACD
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACD (RC204381, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ACD.
TA504379 - ACD
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ACD mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA504379)
TA504379 - ACD
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-ACD mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA504379)
TA504379 - ACD
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-ACD mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA504379)
TA504379 - ACD
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-ACD mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA504379)
TA504379 - ACD
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACD (RC204381, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ACD.
TA504379 - ACD
Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-ACD monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
TA504406 - ACD
Anti-ACD mouse monoclonal antibody (TA504406) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD(RC204381).
TA504406 - ACD
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACD (RC204381, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ACD.
TA504406 - ACD
HEK293T cells transfected with either RC204381 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-ACD antibody(TA504406), and then analyzed by flow cytometry.
TP304381 - ACD
TP316277 - ACD
TA341742 - ACD
WB Suggested Anti-Acd Antibody Titration: 0.2-1 ug/ml; Positive Control: Mouse Muscle
TA344400 - ACD
WB Suggested Anti-ACD Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human brain
TA344401 - ACD
WB Suggested Anti-ACD Antibody Titration: 0.2-1 ug/ml; Positive Control: NCI-H226 cell lysate
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14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ACD antibody
  ACD mouse monoclonal antibody, clone OTI2B1 (formerly 2B1)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ACD mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA504379) Mouse IgG1 OTI2B1 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.
+5 additional images

Highly validated antibody!

TrueMAB

ACD antibody
  ACD mouse monoclonal antibody, clone OTI1C8 (formerly 1C8)  
Anti-ACD mouse monoclonal antibody (TA504201) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD(RC204381). Mouse IgG2b OTI1C8 Purified Hu ICC/IF, WB
0.1 ml / €360.00
  OriGene Technologies, Inc.
+1 additional image

TrueMAB

ACD antibody
  ACD mouse monoclonal antibody, clone OTI1A2 (formerly 1A2)  
Anti-ACD mouse monoclonal antibody (TA504406) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD(RC204381). Mouse IgG1 OTI1A2 Purified Hu F, ICC/IF, WB
0.1 ml / €360.00
  OriGene Technologies, Inc.
+2 additional images

TrueMAB

CRISPR

Catalog No. Species Donor Vector  

ACD - human gene knockout kit via CRISPR
ACD - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACD - human gene knockout kit via CRISPR
ACD - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACD - human gene knockout kit via CRISPR
ACD - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACD - human gene knockout kit via CRISPR
ACD - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ACD (transcript variant 1)
  Recombinant protein of human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 1  
ACD Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

ACD (transcript variant 2)
  Recombinant protein of human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 2  
ACD Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

Lysates

Catalog No.    

ACD overexpression lysate
ACD overexpression lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

ACD overexpression lysate
ACD overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

ACD overexpression lysate
ACD overexpression lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Acd (GFP-tagged ORF) - Rat adrenocortical dysplasia homolog (mouse) (Acd), 200 uL, >10^7 TU/mL
Lenti ORF particles, Acd (GFP-tagged ORF) - Rat adrenocortical dysplasia homolog (mouse) (Acd), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Acd (Myc-DDK-tagged ORF) - Rat adrenocortical dysplasia homolog (mouse) (Acd), 200 uL, >10^7 TU/mL
Lenti ORF particles, Acd (Myc-DDK-tagged ORF) - Rat adrenocortical dysplasia homolog (mouse) (Acd), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

14 Item(s)

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  1. CRISPR (4)
  2. Lysate (3)
  3. Primary Antibody (3)
  4. Protein | Growth Factor (2)
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  1. Monoclonal (3)
Target
  1. ACD (5)
Reactivity
  1. Human (Hu) (3)
Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  3. Flow cytometry (F) (1)
  4. Paraffin Sections (P) (1)
Presentation
  1. Purified (3)
Host
  1. Mouse (3)
Images
  1. 1 image (5)
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  3. 5+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  3. Flow cytometry (F) (1)
  4. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (2)
Source
  1. HEK293 cells (2)
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  1. Human (4)
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  1. GFP-Puro (1)
  2. Luciferase-Puro (1)
  3. RFP-BSD (1)
  4. mBFP-Neo (1)
Manufacturer
  1. OriGene Technologies (14)
Service
  • OriGene Technologies GmbH
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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