Adenovirus Type 2 E1A antibody
Principal name
Adenovirus Type 2 E1A antibody
Alternative names for Adenovirus Type 2 E1A antibody
Adenovirus Early Region 1, Early E1A 32 kDa protein
SwissProt ID
P03254 (Ade02)
Ncbi ID
Available reactivities
Available hosts
Available applications
Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of Adenovirus Type 2 E1A antibody
The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary Cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
General readings
1. Harlow E. et. al. (1986) Association of adenovirus early region 1A proteins with cellular
peptides) Mol. Cell Biol., 6 1579-1589.
2. Harlow, E. et. al. (1985) Monoclonal antibodies specific for adenovirus E1A proteins: extensive heterogeneity in the E1A products J. Virology 3: 533-546.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AM05218PU-N | Adenovirus Type 2 E1A antibody |
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Mouse | IgG2a | M73 | Purified | ICC/IF, IP |
0.1 mg /
€400.00
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| OriGene Technologies GmbH | |||||||