ALAD antibody
Principal name
ALAD antibody
Alternative names for ALAD antibody
Delta-aminolevulinic acid dehydratase, ALADH, Porphobilinogen synthase
Ncbi ID
9606, NP_001003945, NP_000022, NP_000022.3, BC018236, NM_012899, NM_000031
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))
Background of ALAD antibody
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
General readings
Li,C.. et al. (2011) Toxicol. Lett. 203 (1), 48-53van Bemmel et al. (2011) Epidemiology 22 (2), 273-278
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP17099PU-N | ALAD (C-term) antibody |
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 |
Rabbit | Hu | WB |
0.4 ml /
€415.00
|
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| OriGene Technologies GmbH | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP301545 | ALAD |
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| Recombinant protein of human aminolevulinate, delta-, dehydratase (ALAD) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR201832L2V | Lenti ORF particles, Alad (GFP-tagged) - Mouse aminolevulinate, delta-, dehydratase (cDNA clone MGC:18970 IMAGE:3992605), 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€840.00
|
|
| OriGene Technologies, Inc. | ||
| MR201832L1V | Lenti ORF particles, Alad (Myc-DDK-tagged) - Mouse aminolevulinate, delta-, dehydratase (cDNA clone MGC:18970 IMAGE:3992605), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€740.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR204880L2V | Lenti ORF particles, Alad (GFP-tagged ORF) - Rat aminolevulinate, delta-, dehydratase (Alad), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| RR204880L1V | Lenti ORF particles, Alad (Myc-DDK-tagged ORF) - Rat aminolevulinate, delta-, dehydratase (Alad), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||